Expertise
Interaction of biomolecules
Description:
This platform involves several devices mainly applied for:
- Characterization of structure and dynamic of the assembly of cellular and membrane multi-protein complexes
- Study of molecule/membrane interactions, membrane penetration and biomolecules internalization,
- Analysis of biological nano-objects and/or protein complexes.
- Secondary structure of peptides, proteins and oligonucleotides,
- Lipid membranes /molecules interactions,
- Physicochemical and thermal stability of peptides, proteins and antibodies.
- Lipid monolayers,
- Membranes/biomolecules interactions (lipid monolayers insertion),
- Biomolecules amphipathicity.
- Nano-objects size and polydispersity by dynamic light scattering (DLS) analysis,
- Surface charge by Zeta potential measurements,
- Protein complexes stability.
- Biomolecules interactions by fluorescence monitoring,
- Protein complexes formation and affinity measurements,
- Molecules/membranes interactions by fluorescence measurements.
