Research program : Respiratory diseases and the environment

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Program

The quality of the air we breathe has a major impact on our health, particularly on the pulmonary system, with consequences for the cardiovascular and muscular systems. In a context of multiple, complex and changing environmental exposures, the objective of our team is to understand why some are protected and others develop respiratory failure. Through clinical and fundamental studies on animal and cellular models, we study the physiological, molecular and epigenetic mechanisms responsible for alterations in heart-lung interactions and in the development of muscular and vascular comorbidities for respiratory pathologies in response to specific exhibitions.

Axes

Project 1 – Origins and consequences of inflammatory profiles in chronic respiratory diseases

Epigenetics and Chronic Lung Diseases: COPD and Cystic Fibrosis

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Air pollution and pulmonary emphysema: impacts on cardiovascular hemodynamics

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Air pollution and pulmonary emphysema: impacts on skeletal muscle function

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Responders and non-responders in the clinic

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Responders and non-responders to new ex vivo therapies

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